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Home page > Séminaires > Séminaires 2020 > Séminaire MSC. 13 Janvier 2020. Gregory Lavieu ( INSERM U932/Institut Curie, Paris). "Extracellular Vesicle Uptake & Delivery : Cellular and Molecular Aspects.".

Séminaire MSC. 13 Janvier 2020. Gregory Lavieu ( INSERM U932/Institut Curie, Paris). "Extracellular Vesicle Uptake & Delivery : Cellular and Molecular Aspects."

Sauf mention contraire, les séminaires et les soutenances se déroulent à 11h30 en salle 454A du bâtiment Condorcet.


Extracellular Vesicle Uptake & Delivery : Cellular and Molecular Aspects

Grégory Lavieu INSERM U932/Institut Curie, Paris

Abstract : Extracellular Vesicles (EVs), including exosomes, are thought to mediate intercellular communication through the transfer of biomolecules from donor to acceptor cells. Occurrence of EV-content delivery has never been unambiguously demonstrated, let alone quantified, and remains debated. We developed a cell-based and cell-free assay to track the fate of EV-cargo in acceptor cells. Our results suggest that EV-content delivery requires endosomal acidification and the involvement of membrane fusion.


Contact : Équipe séminaires / Seminar team - Published on / Publié le 8 janvier