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Home page > Séminaires > Séminaires 2022 > MSC Visio-Seminar. March 7th 2022 at 11:30. Pierre-François Lenne (Aix Marseille University, CNRS) : " From cell generated forces to global tissue pattern and shape (and back)".

MSC Visio-Seminar. March 7th 2022 at 11:30. Pierre-François Lenne (Aix Marseille University, CNRS) : " From cell generated forces to global tissue pattern and shape (and back)"

Sauf mention contraire, les séminaires et les soutenances se déroulent à 11h30 en salle 454A du bâtiment Condorcet.


There will be a live diffusion with Zoom.

Monday March 7th, 11h30

Contact Jean-Baptiste Manneville to attend the visio-seminar

From cell generated forces to global tissue pattern and shape (and back)

Pierre-François Lenne IBDM, Turing Center for Living Systems Aix Marseille University, CNRS

How shapes of organs and organisms emerge from the interaction of cells has been a central question of the past decades. This question has been mainly formulated with the strong assumption that cells are assigned with physical properties and rules of interactions that guide how they arrange and grow to form functional structures. In this context I will show our attempts to relate cell mechanics to tissue shape, using the Drosophila embryo as a model system. I will discuss several aspects of cell contacts mechanics : the importance of geometry, the time dependence of material properties, and feedback between adhesion and cytoskeletal mechanics. I will also show how collective cell movement and cell-state transitions cooperate to pattern and shape minimal self-organized multicellular systems that mimic early mammalian morphogenesis.


Contact : Équipe séminaires / Seminar team - Published on / Publié le 22 février


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