Partenaires

MSC
Logo CNRS Logo Université Paris Diderot
Logo tutelle Logo tutelle



Поиск

Sur ce site

Sur le Web du CNRS


На главную > Séminaires > Archives séminaires > Séminaires 2014 > Séminaire MSC. Jeudi 10 Avril 2014. Julien Dervaux (LIED, Université Paris Diderot) : "On growth and form of Bacillus Subtilis biofilms.".

Séminaire MSC. Jeudi 10 Avril 2014. Julien Dervaux (LIED, Université Paris Diderot) : "On growth and form of Bacillus Subtilis biofilms."

Sauf mention contraire, les séminaires et les soutenances se déroulent à 11h30 en salle 454A du bâtiment Condorcet.


On growth and form of Bacillus Subtilis biofilms.

Julien Dervaux : LIED, Université Paris Diderot

Attention horaire exceptionnel : jeudi 10 avril à 16h00 en salle 454A Le séminaire prévu le 7 avril est reporté au 10 en raison de la journée fluides actifs du GDR Mephy.

A general feature of mature biofilms is their highly heterogeneous architecture that partitions the microbial city into sectors with specific micro-environments. To understand how this heterogeneity arises, I have investigated the sequence of events leading from a single cell to a fully developed microbial community of the model organism Bacillus subtilis. To trigger biofilm assembly, I show that an initially single cell must produce a cellular cluster of 650 microns squared, irrespectively of the environmental parameters (substrate stiffness and nutrient concentration). Once present, matrix producing cells tend to stay connected with their lineage after division and long bacterial chains form. This morphological transition gives rise to a mechanism of front propagation that qualitatively differs from that of short, rod-shape, undifferentiated cells. In addition to the process of cellular chaining, the biomass stickiness also strongly hinders the reorganization of cells within the biofilm. As a consequence, local height fluctuations of the growing bacterial layer coarsen in time and ultimately lead to the formation of a rough biofilm surface exhibiting self similar properties. A biophysical model associating the nonlocality and the stochasticity of the growth process reproduces the experimental features.


Contact : Équipe séminaires / Seminar team - Published on / Publié le 11 février 2014


Dans la même rubrique :