Startseite > Séminaires > Archives séminaires > Séminaires 2015 > Séminaire MSC. Lundi 2 Février à 11h30. Elisha Moses (Weizmann Institute) : "Dynamics in Networks of Cultured Neurons".
Sauf mention contraire, les séminaires et les soutenances se déroulent à 11h30 en salle 454A du bâtiment Condorcet.
Lundi 2 Février à 11h30
Elisha Moses
Institute for Complex Systems, Weizmann Institute
Dynamics in Networks of Cultured Neurons
Cultured networks of neurons from rat hippocampus constitute a fascinating reductionist model for biological computation. While the individual neurons retain their physiological characteristics as in the intact brain, the structure and connectivity they generate in the network is considerably simpler to measure and analyze, and therefore to engineer and design. We describe three systems of neurons, unraveling both network structure and single neuron properties that underlie dynamics in these cultures. In a 1D geometry propagation of activity and of information underlies a minimal computational capability. In 2D excitation is dominated by a percolation process in which a quorum is recruited for exciting a single neuron. We end by using this approach to show that pathology in neurons from Down Syndrome mice models is dominated by perturbed potassium channel regulation.
Elisha Moses est professeur invité au laboratoire MSC durant le mois de Février dans l’équipe Neuro-physique (Bottani, Monceau, Métens)
Contact : Équipe séminaires / Seminar team - Published on / Publié le 13 janvier 2015
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