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Startseite > Séminaires > Archives séminaires > Séminaires 2015 > Seminaire MSC. Lundi 16 novembre 2015. Marie-Cécilia DUVERNOY. LPS ENS. Mécanique de croissance d’une micro-colonie bactérienne..

Seminaire MSC. Lundi 16 novembre 2015. Marie-Cécilia DUVERNOY. LPS ENS. Mécanique de croissance d’une micro-colonie bactérienne.

Sauf mention contraire, les séminaires et les soutenances se déroulent à 11h30 en salle 454A du bâtiment Condorcet.

The morphology of mature biofilms have been reported to adapt to environmental challenges. Yet, if some proteins influencing the shape have been identified, mechanisms by which those shapes are modulated are barely known. In particular, early steps of biofilm formation are critical as bacteria have to proliferate while maintaining contact on the surface they colonize. Using timelapse force microscopy of E. coli and P. aeruginosa microcolonies, we show that adhesions are heterogeneous and dynamical. Moreover, at the single cell level, adhesions tend to localize at the old pole of cells. Experiments using adhesion mutant strains as well as simulations show that the cellular localization of adhesions as well as their strength determine the shape of two-dimensional microcolonies and trigger their transition to a three-dimensional growth regime. This study propose the interaction with the surface as a major levier by which rod-shape bacteria module the shape of their group.

Contact : Équipe séminaires / Seminar team - Published on / Publié le 4 novembre 2015

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