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Accueil du site > Seminars > Séminaires théorie > Theory Club Friday June 14 at 12:30pm in room 646A. David Lacoste: "From transient compartmentalization to cell population dynamics" {{From transient compartmentalization to cell population dynamics}}.

Theory Club Friday June 14 at 12:30pm in room 646A. David Lacoste: "From transient compartmentalization to cell population dynamics" {{From transient compartmentalization to cell population dynamics}}

Unless otherwise stated, seminars and defences take place at 11:30 in room 454A of Condorcet building.


From transient compartmentalization to cell population dynamics

David Lacoste

Abstract: From transient compartmentalization to cell population dynamics

In the fifties, Oparin imagined liquid-like compartments called coacervates, which could have played a central role in the origin of life [1]. Although the experimental verification of this idea remained scarce for many years, the idea resurfaced recently in various systems of biological interest in which liquid non-membrane compartments were found. An important aspect not tested in the Oparin scenario is the role of the transient nature of compartmentalization. Here, we discuss a general class of multilevel selection with transient compartmentalization [2], and its robustness against noise and mutations [3]. We argue that transient compartmentalization represents a more generic and simple mechanism for the Origin of life as compared to alternate scenarios based on cell division. In a second part, time permitting, I will present a different project related to a study of cell growth and cell division in a population of growing cells [4].

- [1] Origin of life, A. I. Oparin (1952).
- [2] Selection dynamics in transient compartmentalization, A. Blokhuis, D. L., P. Nghe, L. Peliti, Phys. Rev. Lett. 120, 158101 (2018).
- [3] Transient compartmentalization dynamics in the presence of mutations and noise, A. Blokhuis, P. Nghe, L. Peliti and D. L., under review, https://arxiv.org/abs/1901.04753
- [4] Linking lineage and population observables in biological branching processes, R. Garcia-Garcia, A. Genthon and D. L., Phys. Rev. E, 99, 042413 (2019)

Friday June 14 at 12:30pm in room 646A


Contact : Équipe séminaires / Seminar team - Published on / Publié le 29 May


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